Transcriptional impacts of substance use disorder and HIV on human ventral midbrain neurons and microglia
Alyssa Michelle Wilson, Michelle M. Jacobs, Tova Y. Lambert, Aditi Valada, Gregory Meloni, Evan Gilmore, Jacinta Murray, Susan Morgello, Schahram Akbarian
This study examines how HIV and substance use disorders affect gene expression in human ventral midbrain neurons and microglia, identifying transcriptional changes linked to disease comorbidities.
Nature Communications · Oct 14, 2025Peer-reviewedGenomics