Author

Michelle M. Jacobs

Icahn School of Medicine at Mount SinaiORCID 0009-0003-0950-3237Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Aditi ValadaiD· 1 shared Alyssa Michelle WilsoniD· 1 shared Evan Gilmore· 1 shared Gregory Meloni· 1 shared Jacinta Murray· 1 shared Schahram AkbarianiD· 1 shared Susan MorgelloiD· 1 shared Tova Y. LambertiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperGenomics

Aditi ValadaORCID

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1 paper

Recent·Most cited

GenomicsNature CommunicationsPeer-reviewedOct 14, 2025

Transcriptional impacts of substance use disorder and HIV on human ventral midbrain neurons and microglia

Alyssa Michelle Wilson, Michelle M. Jacobs, Tova Y. Lambert…·Schahram Akbarian

This study examines how HIV and substance use disorders affect gene expression in human ventral midbrain neurons and microglia, identifying transcriptional changes linked to disease comorbidities.

4 citations

humanscRNA-seq

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