Alyssa Michelle Wilson

This study examines how HIV and substance use disorders affect gene expression in human ventral midbrain neurons and microglia, identifying transcriptional changes linked to disease comorbidities.

This study investigates synaptic connectivity development in the mouse cerebellum, revealing sequential input-dependent wiring and individualized parallel fiber inputs to Purkinje cells.

The paper maps synaptic connectivity between cortical pyramidal neurons and shows synapse size is modeled by a combination of binary and analog variables.

The paper uses 3D reconstruction and deep learning to reveal intercellular connections between developing granule cells in the cerebellar EGL, showing a continuum of proliferative and migratory events.

This paper introduces SynapseCLR, a contrastive learning method for 3D EM data to extract synapse features from mouse visual cortex, achieving high accuracy in synapse classification and annotation.

The paper identifies oligodendrocyte precursor cells (OPCs) as major contributors to axon pruning in the mouse neocortex through phagocytic activity.

The paper presents a semi-automated reconstruction of mouse primary visual cortex from electron microscopy data, revealing structural and functional relationships in cortical circuits.

The paper shows that during cerebellar development, climbing fibers add synapses to a subset of Purkinje cells through positive feedback, without pruning other connections, and that this process is economical due to matching axon and Purkinje cell numbers.