Author

Jacinta Murray

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1

Frequent Co-Authors

Aditi ValadaiD· 2 shared Schahram AkbarianiD· 2 shared Susan MorgelloiD· 2 shared Tova Y. LambertiD· 2 shared Alyssa Michelle WilsoniD· 1 shared Amara L. Plaza-JenningsiD· 1 shared Behnam JavidfariD· 1 shared Benjamin K. CheniD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersGenomics

Aditi ValadaORCID

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2 papers

Recent·Most cited

Transcriptional impacts of substance use disorder and HIV on human ventral midbrain neurons and microglia

Alyssa Michelle Wilson, Michelle M. Jacobs, Tova Y. Lambert, Aditi Valada, Gregory Meloni, Evan Gilmore, Jacinta Murray, Susan Morgello, Schahram Akbarian

This study examines how HIV and substance use disorders affect gene expression in human ventral midbrain neurons and microglia, identifying transcriptional changes linked to disease comorbidities.

Nature Communications · Oct 14, 2025Peer-reviewedGenomics

HIV integration in the human brain is linked to microglial activation and 3D genome remodeling

Amara L. Plaza-Jennings, Aditi Valada, Callan P. O’Shea, Marina Iskhakova, Benxia Hu, Behnam Javidfar, Gabriella Ben Hutta, Tova Y. Lambert, Jacinta Murray, Bibi S. Kassim, Sandhya Chandrasekaran, Benjamin K. Chen, Susan Morgello, Hyejung Won, Schahram Akbarian

The paper examines HIV integration in the human brain using single nuclei transcriptomics, Hi-C, and IS-seq, finding 3D genomic reorganization and microglial activation linked to HIV infection.

Molecular Cell · Dec 1, 2022Peer-reviewedNeuroscience