Author

Evan Knep

University of Minnesota

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Animal Behavior & Cognition· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:behavioral assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

Cathy S. CheniD· 3 shared Nicola M. GrissomiD· 3 shared R. Becket EbitziD· 3 shared Angelica Velosa· 2 shared Dana MuelleriD· 2 shared Erin Giglio· 2 shared Patrick E. RothwelliD· 2 shared Sarah R. HeilbronneriD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersAnimal Behavior & Cognition

Cathy S. ChenORCID

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3 papers

Recent·Most cited

NMDA receptor ablation in medial prefrontal cortex disrupts value updating and reward history integration

Evan Knep, Angelica Velosa, Dana Mueller, Cathy S. Chen, Sophia Vinogradov, Matthew V. Chafee, R. Becket Ebitz, Sarah R. Heilbronner, Patrick E. Rothwell, Nicola M. Grissom

This study shows that NMDA receptor loss in the medial prefrontal cortex impairs value updating and reward history integration in mice, mimicking schizophrenia-like cognitive deficits.

Neuropsychopharmacology · Sep 1, 2026Peer-reviewedNeuroscience

Sex-biased computations underlying differential set shift performance in mice

Nic Glewwe, Evan M. Dastin-van Rijn, Cathy S. Chen, Erin Giglio, Evan Knep, R. Becket Ebitz, Alik S. Widge, Nicola M. Grissom

The paper investigates sex differences in cognitive flexibility using a novel touchscreen Set Shift task in mice, finding females perform better with fewer errors and distinct computational strategies.

Neuropsychopharmacology · Apr 10, 2026Peer-reviewedAnimal Behavior & Cognition

16p11.2 duplication shows early male-biased impacts on reward learning, but NMDA receptor antagonism reduces optimal choice selection in both wildtypes and 16p11.2 duplication

Dana Mueller, Evan Knep, Angelica Velosa, Erin Giglio, Cathy S. Chen, Sarah R. Heilbronner, R. Becket Ebitz, Patrick E. Rothwell, Nicola M. Grissom

This study examines how 16p11.2 duplication affects reward learning in mice, finding male-biased impacts in early training but no genotype effect in a bandit task, while NMDAR antagonism impairs choice flexibility in all animals.

bioRxiv · Jun 28, 2025 · PreprintAnimal Behavior & Cognition