Cathy S. Chen

This study shows that NMDA receptor loss in the medial prefrontal cortex impairs value updating and reward history integration in mice, mimicking schizophrenia-like cognitive deficits.

This study compares persistence in decision-making across mice, monkeys, and humans in a dynamic task, finding that primates outlast mice in exploitation strategies.

The paper investigates sex differences in cognitive flexibility using a novel touchscreen Set Shift task in mice, finding females perform better with fewer errors and distinct computational strategies.

This study examines how 16p11.2 duplication affects reward learning in mice, finding male-biased impacts in early training but no genotype effect in a bandit task, while NMDAR antagonism impairs choice flexibility in all animals.

This paper introduces a foraging-theory-based model that better captures human behavioral diversity in sequential decision-making compared to traditional value-comparison models.

This study shows that touchscreen response precision in mice is influenced by explore/exploit state, reward history, and individual differences, reflecting subjective certainty in reward-guided decision making.