Nicola M. Grissom

This study shows that NMDA receptor loss in the medial prefrontal cortex impairs value updating and reward history integration in mice, mimicking schizophrenia-like cognitive deficits.

This study compares persistence in decision-making across mice, monkeys, and humans in a dynamic task, finding that primates outlast mice in exploitation strategies.

The paper investigates sex differences in cognitive flexibility using a novel touchscreen Set Shift task in mice, finding females perform better with fewer errors and distinct computational strategies.

This study investigates how NMDAR ablation in adolescent mice affects synaptic structure and function in the medial prefrontal cortex, revealing early disruption followed by compensatory recovery.

This study examines how 16p11.2 duplication affects reward learning in mice, finding male-biased impacts in early training but no genotype effect in a bandit task, while NMDAR antagonism impairs choice flexibility in all animals.

This paper introduces a foraging-theory-based model that better captures human behavioral diversity in sequential decision-making compared to traditional value-comparison models.

This study shows that touchscreen response precision in mice is influenced by explore/exploit state, reward history, and individual differences, reflecting subjective certainty in reward-guided decision making.

The paper identifies a dominant nonlinear axis of individual variability in decision-making tasks, showing that exploration tendency, rather than personality or learning parameters, drives differences in performance.

This study identifies distinct computational mechanisms of uncertainty processing in anxiety and apathy, showing how they influence exploratory behaviors through different perceptions of volatility and stochasticity.

This study investigates sex differences in morphine sensitivity in neuroligin-3 knockout mice, finding distinct effects in males and females.

The paper identifies a low-dimensional behavioral manifold that captures exploration-exploitation decision-making and links it to symptoms of apathy and anxiety.