Hunting for microsatellite instability in long-read data with Owl
Zev N. Kronenberg, Byunggil Yoo, Khi Pin Chua, Mark Chaisson, Lisa A. Lansdon, William J. Rowell, Guilherme De Sena Brandine, Jocelyne Bruand, Egor Dolzhenko, Kobe Ikegami, Jay Sarthy, Kie Kyon Huang, Everett T Fan, Shruti Bhise, Everett Fan, , Michael A. Eberle
Owl quantifies microsatellite instability from long-read data, identifying MSI-high genomes and motif-specific patterns in cancer samples.
PLoS Computational Biology · Sep 2, 2026Peer-reviewedBioinformatics