Sub-3 Angstrom cryo-EM structure of RNA enabled by engineered homomeric self-assembly
D. Liu, F. A. Thelot, J. A. Piccirilli, M. Liao, P. Yin
This paper introduces a method to improve cryo-EM analysis of RNA structures by engineering kissing-loop sequences for homomeric assembly, achieving high-resolution reconstructions of RNA molecules.
bioRxiv · Aug 11, 2021Biophysics