Pathogenic neutrophilia drives acute respiratory distress syndrome in severe COVID-19 patients
D. J. Eddins, J. Yang, A. Kosters, V. Giacalone, X. Pechuan, J. D. Chandler, J. Eum, B. R. Babcock, B. S. Dobosh, M. R. Hernandez, F. Abdulkhader, G. L. Collins, R. P. Ramonell, C. Moussion, D. Orlova, , E. Ghosn
The paper identifies pathogenic neutrophilia as a driver of acute respiratory distress syndrome in severe COVID-19 patients, highlighting IL-8/CXCR2-mediated neutrophil recruitment and hyperinflammation.
bioRxiv · Jun 2, 2021 · PreprintImmunology