Author

X. Pechuan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Bergman· 1 shared A. Kosters· 1 shared B. R. Babcock· 1 shared B. S. Dobosh· 1 shared C. Eidenschenk· 1 shared C. Everett· 1 shared C. Lu· 1 shared C. Moussion· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperEvolutionary Biology

A. Bergman

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Loss of the intracellular enzyme QPCTL limits chemokine function and reshapes myeloid infiltration to augment tumor immunity

R. Barreira da Silva, R. Leitao, X. Pechuan, S. Werneke, J. Oeh, V. Javinal, Y. Wang, W. Phung, C. Everett, J. Nonomiya, D. Arnott, C. Lu, Y.-C. Hsiao, J. T. Koerber, I. Hotzel, , M. Albert

This study shows that QPCTL inhibition reduces monocyte migration and alters myeloid cell infiltration, enhancing anti-tumor immunity when combined with anti-PD-L1 therapy.

bioRxiv · Jan 25, 2022Immunology

Pathogenic neutrophilia drives acute respiratory distress syndrome in severe COVID-19 patients

D. J. Eddins, J. Yang, A. Kosters, V. Giacalone, X. Pechuan, J. D. Chandler, J. Eum, B. R. Babcock, B. S. Dobosh, M. R. Hernandez, F. Abdulkhader, G. L. Collins, R. P. Ramonell, C. Moussion, D. Orlova, , E. Ghosn

The paper identifies pathogenic neutrophilia as a driver of acute respiratory distress syndrome in severe COVID-19 patients, highlighting IL-8/CXCR2-mediated neutrophil recruitment and hyperinflammation.

bioRxiv · Jun 2, 2021 · PreprintImmunology

Evolutionary contingency’s impact on laboratory evolution of Escherichia coli under fluctuating environments

X. Pechuan, D. Biro, M. Lambros, A. Bergman

This study evolves Escherichia coli under fluctuating temperature regimes to examine evolutionary contingency and adaptation strategies, finding distinct genetic and phenotypic responses depending on initial genetic background.

bioRxiv · Apr 5, 2019 · PreprintEvolutionary Biology