Author

F. C. Gherardini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

W. K. Boyle· 2 shared A. Groshong· 1 shared A. K. Zalud· 1 shared A. S. Gupta· 1 shared C. L. Richards· 1 shared C. Richards· 1 shared D. Drecktrah· 1 shared D. M. Monack· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersMicrobiology

W. K. Boyle

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Author profile →

3 papers

Recent·Most cited

Metabolomic analysis of diverse mice reveals hepatic arginase-1 as source of plasma arginase in Plasmodium chabaudi infection

N. M. Davis, M. M. Lissner, L. M. Massis, C. L. Richards, V. Chevee, A. S. Gupta, F. C. Gherardini, D. M. Monack, D. S. Schneider

The paper uses metabolomic analysis in diverse mice to show that liver damage during Plasmodium chabaudi infection releases hepatic arginase-1 into plasma, contributing to arginine depletion.

bioRxiv · Jun 11, 2021Pathology

DksA-dependent regulation of RpoS contributes to Borrelia burgdorferi tick-borne transmission and mammalian infectivity

W. K. Boyle, C. Richards, D. P. Dulebohn, A. K. Zalud, J. A. Shaw, S. Lovas, F. C. Gherardini, T. J. Bourret

This study shows DksA regulates RpoS-dependent gene expression in B. burgdorferi, essential for tick transmission and mammalian infectivity, through interactions with RNA polymerase and post-transcriptional control of RpoS.

bioRxiv · Nov 4, 2020Microbiology

DksA controls the response of the Lyme disease spirochete Borrelia burgdorferi to starvation

W. K. Boyle, A. Groshong, D. Drecktrah, J. A. Boylan, J. S. Blevins, S. Samuels, F. C. Gherardini, T. Bourret

This study shows DksA regulates B. burgdorferi's starvation response by controlling gene expression, with dksA mutants showing reduced survival and altered (p)ppGpp levels.

bioRxiv · Sep 20, 2018Microbiology