N. M. Davis

Exogenous butyrate inhibits butyrogenic metabolism and alters expression of virulence genes in Clostridioides difficile

This study shows exogenous butyrate inhibits C. difficile growth by interfering with its own butyrate production and alters virulence gene expression.

Variation in the response to malaria in Diversity Outbred mice

The paper investigates genetic variation in the host response to malaria in Diversity Outbred mice by identifying loci associated with parasite load and mortality.

Metabolomic analysis of diverse mice reveals hepatic arginase-1 as source of plasma arginase in Plasmodium chabaudi infection

The paper uses metabolomic analysis in diverse mice to show that liver damage during Plasmodium chabaudi infection releases hepatic arginase-1 into plasma, contributing to arginine depletion.

Eastern Equine Encephalitis Virus Rapidly Infects and Disseminates in the Brain and Spinal Cord of Infected Cynomolgus Macaques Following Aerosol Challenge

This study investigates EEEV pathogenesis in cynomolgus macaques following aerosol challenge, finding that the virus replicates in the olfactory bulb and spreads via axonal transport, causing neuronal dysfunction rather than death.

Long-term cellulose enrichment selects for highly cellulolytic consortia and competition for public goods

This study shows that long-term cellulose enrichment leads to stable or variable cellulolytic abilities in microbial communities, with competition for public goods affecting decomposition rates.

Microbiota Accessible Carbohydrates Suppress Clostridium difficile in a Murine Model

The paper shows that microbiota accessible carbohydrates (MACs) reduce Clostridium difficile infection in mice by suppressing bacterial burdens.