F. C. Simmel

From Brownian to deterministic motor movement in a DNA-based molecular rotor

This study shows that DNA origami rotors can function as Brownian motors with intrinsic anisotropy, transitioning to deterministic motion under higher external switching fields.

Single-Molecule Force Spectroscopy of Toehold-Mediated Strand Displacement

This study uses single-molecule force spectroscopy to analyze the kinetics of toehold-mediated strand displacement, revealing sequence-dependent dynamics and load effects in DNA and RNA interactions.

Toehold-Mediated Strand Displacement in Random Sequence Pools

This study investigates how random DNA sequences affect toehold-mediated strand displacement circuits and identifies strategies to mitigate their impact.

Microrobots Powered by Concentration Polarization Electrophoresis (CPEP)

The paper demonstrates microrobots powered by concentration polarization electrophoresis, showing they can be steered and used to manipulate particles.

Algorithmic design of 3D wireframe RNA polyhedra

The paper introduces an algorithmic design process and software pipeline for creating 3D wireframe RNA polyhedra, validated through experimental characterization of three structures.

Bacterial growth, communication and guided chemotaxis in 3D bioprinted hydrogel environments

This study develops a bioprinting method for 3D hydrogel structures containing live E. coli bacteria, enabling controlled chemical communication and chemotaxis guidance.

A synthetic tubular molecular transport system

This paper constructs a synthetic tubular molecular transport system using DNA origami and demonstrates its diffusive motion and mobility improvements over previous artificial designs.

A low-cost fluorescence reader for in vitro transcription and nucleic acid detection with Cas13a

The paper develops a low-cost fluorescence reader for POCT, capable of detecting nanomolar concentrations of fluorescein and demonstrating RNA transcription and Cas13a-based RNA detection.