Author

M. Lenz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 5 Bioengineering· 2 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 9 Research Focus:cell signaling & trafficking· 5 Assay:fluorescence / live-cell microscopy· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Roux· 2 shared L. Barberi· 2 shared A. Abosch· 1 shared A. Allard· 1 shared A. Dupin· 1 shared A. Fringuello· 1 shared A. Frost· 1 shared A. Graner· 1 shared

Activity by Year

2017-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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2 shared papersBiophysics

A. Roux

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

A tale of two tumors: differential, but detrimental, effects of glioblastoma extracellular vesicles (EVs) on normal human brain cells

M. Wang, A. Graner, B. Knowles, C. McRae, A. Fringuello, P. Paucek, M. Gavrilovic, M. Redwine, C. Coughlan, C. Hanson, B. Metzger, V. Bolus, T. Kopper, M. Smith, W. Zhou, , M. W. Graner

This study shows that glioblastoma extracellular vesicles induce different transcriptomic, secretomic, and proteomic effects on normal brain cells, yet all lead to increased tumorigenicity.

bioRxiv · Apr 8, 2024 · PreprintCancer Biology

On-chip brain slice stimulation: precise control of electric fields and tissue orientation

S. Shaner, H. Lu, M. Lenz, S. Garg, A. Vlachos, M. Asplund

This paper develops an on-chip platform for precise control of electric fields and tissue orientation in brain slice stimulation to better study the effects of direct current stimulation.

bioRxiv · Apr 13, 2023 · PreprintBioengineering

Fragmentation and entanglement limit vimentin intermediate filament assembly

Q. D. Tran, V. Sorichetti, G. Pehau-Arnaudet, M. Lenz, C. Leduc

This study investigates vimentin intermediate filament assembly dynamics, revealing that fragmentation and entanglement influence assembly and disassembly, with fragmentation occurring independently of post-translational modifications.

bioRxiv · Mar 19, 2022Biophysics

Local structure of DNA toroids reveals curvature-dependent intermolecular forces

L. Barberi, F. Livolant, A. Leforestier, M. Lenz

The paper uses cryo-EM to study DNA toroids and finds curvature-dependent intermolecular forces that differ from bulk measurements.

Nucleic Acids Research · Apr 19, 2021Peer-reviewedBiophysics

Quantitative coupling of cell volume and membrane tension during osmotic shocks

C. Roffay, G. Molinard, K. Kim, V. Barbarassa, M. Urbanska, V. Mercier, J. Garcia Calvo, S. Matile, J. Guck, M. Lenz, A. Roux

This study quantifies how cell volume and membrane tension change during osmotic shocks and shows they are coupled but not entirely independent.

bioRxiv · Jan 22, 2021Biophysics

Anisotropic ESCRT-III architecture governs helical membrane tube formation

J. Moser von Filseck, L. Barberi, N. Talledge, I. Johnson, A. Frost, M. Lenz, A. Roux

The paper describes how ESCRT-III filaments assemble into helical membrane tubes through anisotropic architecture and mathematical modeling.

bioRxiv · Jul 26, 2019Biochemistry

Actin modulates shape and mechanics of tubular membranes

A. Allard, M. Bouzid, T. Betz, C. Simon, M. Abou-Ghali, J. Lemiere, F. Valentino, J. Manzi, F. Brochard-Wyart, K. Guevorkian, J. Plastino, M. Lenz, C. Campillo, C. Sykes

This study investigates how actin affects the shape and mechanical stability of tubular membranes by observing actin sleeve growth on preformed membrane tubes.

bioRxiv · Jul 23, 2019Biophysics

A low-cost fluorescence reader for in vitro transcription and nucleic acid detection with Cas13a

F. Katzmeier, L. Aufinger, A. Dupin, J. Quinteiro, M. Lenz, L. Bauer, S. Klumpe, D. Sherpa, B. Dürr, M. Honemann, I. Styazhkin, F. C. Simmel, M. Heymann

The paper develops a low-cost fluorescence reader for POCT, capable of detecting nanomolar concentrations of fluorescein and demonstrating RNA transcription and Cas13a-based RNA detection.

bioRxiv · Jul 12, 2019Bioengineering

Modulation of formin processivity by profilin and mechanical tension

M. Kerleau, L. Cao, E. Suzuki, H. Wioland, S. Jouet, B. Guichard, M. Lenz, G. Romet-Lemonne, A. Jegou

This study investigates how profilin and mechanical tension modulate formin mDia1 processivity by altering dissociation rates from actin filaments.

bioRxiv · Dec 16, 2017Biophysics