Sirolimus plus nintedanib treats vascular pathology in HHT mouse models
S. Ruiz, H. Zhao, P. Chandakkar, J. Papoin, H. Choi, A. Nomura-Kitabayashi, R. Patel, M. Gillen, L. Diao, P. Chatterjee, M. He, Y. Al-Abed, P. Wang, C. Metz, S. P. Oh, , P. Marambaud
This study shows that combining sirolimus and nintedanib treats vascular abnormalities in HHT mouse models by targeting multiple pathways.
bioRxiv · Aug 18, 2019 · PreprintCell Biology