Author

Y. Al-Abed

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Immunology· 2 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 5 Research Focus:cell signaling & trafficking· 3 Assay:electrophysiology· 3 Organism:rat· 3 Research Focus:development & morphogenesis· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

S. Zanos· 4 shared I. T. Mughrabi· 3 shared T. Datta-Chaudhuri· 3 shared Y.-C. Chang· 3 shared A. Abbas· 2 shared B. Diamond· 2 shared B. Sherry· 2 shared L. Rieth· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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4 shared papersBioengineering

S. Zanos

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Intrinsic diving reflex induces potent antioxidative response by activation of NRF2 signaling

K. Powell, S. Wadolowski, W. Tambo, J. J. Strohl, D. Kim, J. Turpin, Y. al-Abed, M. Brines, P. T. Huerta, C. Li

This study shows that both acute and chronic diving reflex activate NRF2 signaling, with acute exposure inducing stronger antioxidative gene expression than chronic exposure.

bioRxiv · Feb 12, 2024 · PreprintPhysiology

Vagus nerve stimulation limits the germinal center B cell response via CD4+ T cell-derived acetylcholine

I. Kurata-Sato, I. T. Mughrabi, M. Rana, M. Gerber, Y. Al-Abed, B. Sherry, S. Zanos, B. Diamond

This study shows that vagus nerve stimulation reduces germinal center B cell responses by affecting CD4+ T cell-derived acetylcholine and its downstream effects on B cell survival and follicular dendritic cell function.

bioRxiv · Oct 25, 2023 · PreprintImmunology

Galantamine Attenuates Autoinflammation in a Mouse Model of Familial Mediterranean Fever

I. T. Mughrabi, M. Ochani, M. Tanovic, P. Wang, B. Diamond, B. Sherry, V. Pavlov, S. Ozen, D. L. Kastner, J. J. Chae, Y. Al-Abed

This study shows galantamine reduces inflammation and disease features in a mouse model of familial Mediterranean fever.

bioRxiv · Jun 10, 2022 · PreprintImmunology

Intermittent KHz-frequency electrical stimulation selectively engages small unmyelinated vagal afferents

Y.-C. Chang, U. Ahmed, N. Jayaprakash, I. Mughrabi, Q. Lin, Y.-C. Wu, M. Gerber, A. Abbas, A. Daytz, A. H. Gabalski, J. Ashville, S. Dokos, L. Rieth, T. Datta-Chaudhuri, K. Tracey, , S. Zanos

This study identifies intermittent KHz-frequency electrical stimulation (KES) as a method to selectively engage small unmyelinated vagal C-afferents in rats and mice.

bioRxiv · Jan 30, 2021 · PreprintBioengineering

Implant- and anesthesia-related factors affecting threshold intensities for vagus nerve stimulation

U. Ahmed, Y.-C. Chang, M. Lopez, J. Wong, T. Datta-Chaudhuri, L. Rieth, Y. Al-Abed, S. Zanos

This study identifies implant- and anesthesia-related factors influencing threshold intensities for vagus nerve stimulation, showing neural thresholds are lower than physiological thresholds and that anesthesia type and implant age significantly affect these thresholds.

bioRxiv · Jan 22, 2021Bioengineering

An implant for long-term cervical vagus nerve stimulation in mice

I. T. Mughrabi, J. Hickman, N. Jayaprakash, E. S. Papadoyannis, A. Abbas, Y.-C. Chang, S. Lee, T. Datta-Chaudhuri, E. H. Chang, T. P. Zanos, R. C. Froemke, C. Welle, Y. Al-Abed, S. Zanos

This paper develops a long-term vagus nerve stimulation implant in mice and demonstrates its effectiveness in reducing inflammation over 4 weeks.

bioRxiv · Jun 20, 2020 · PreprintBioengineering

Sirolimus plus nintedanib treats vascular pathology in HHT mouse models

S. Ruiz, H. Zhao, P. Chandakkar, J. Papoin, H. Choi, A. Nomura-Kitabayashi, R. Patel, M. Gillen, L. Diao, P. Chatterjee, M. He, Y. Al-Abed, P. Wang, C. Metz, S. P. Oh, , P. Marambaud

This study shows that combining sirolimus and nintedanib treats vascular abnormalities in HHT mouse models by targeting multiple pathways.

bioRxiv · Aug 18, 2019 · PreprintCell Biology