Proteomic identification of Axc, a novel beta-lactamase with carbapenemase activity in a meropenem-resistant clinical isolate of Achromobacterxylosoxidans
F. Fleurbaaij, A. A. Henneman, J. Corver, C. W. Knetsch, W. K. Smits, S. T. Nauta, M. Giera, I. Dragan, N. Kumar, T. D. Lawley, A. Verhoeven, H. C. van Leeuwen, E. Kuijper, P. Hensbergen
The paper identifies Axc, a novel beta-lactamase with carbapenemase activity, in a meropenem-resistant Achromobacter xylosoxidans isolate using proteomics and confirms its role in resistance.
bioRxiv · Sep 20, 2017Microbiology