ImmunologybioRxiv
NAMPT-derived NAD+ fuels PARP1 to promote skin inflammation through parthanatos
F. J. Martinez-Morcillo, J. Canton-Sandoval, F. J. Martinez-Navarro…·V. Mulero
This study shows that NAMPT-derived NAD+ fuels PARP1 to drive skin inflammation via parthanatos in psoriasis models.
DOI 10.1371/journal.pbio.3001455