A zebrafish model of COVID-19-associated cytokine storm syndrome reveals differential proinflammatory activities of Spike proteins of SARS-CoV-2 variants of concern.
S. D. Tyrkalska, A. Martinez-Lopez, A. B. Arroyo, F. J. Martinez-Morcillo, S. Candel, P. Mesa-del-Castillo, D. Garcia-Moreno, M. L. Cayuela, V. Mulero
This paper uses a zebrafish model to study the proinflammatory effects of SARS-CoV-2 Spike proteins from different variants, finding differential inflammatory responses and potential therapeutic targets.
bioRxiv · Dec 5, 2021 · PreprintImmunology