TCF7L2 plays a complex role in human adipose progenitor biology which may contribute to genetic susceptibility to type 2 diabetes.
M. Verma, N. Y. Loh, S. K. Vasan, A. D. van Dam, M. Todorcevic, M. J. Neville, F. Karpe, C. Christodoulides
This study investigates TCF7L2's role in adipose progenitor biology and links its genetic variation to type 2 diabetes risk through effects on adipogenesis and insulin sensitivity.
bioRxiv · Nov 26, 2019 · PreprintCell Biology