Author

C. Christodoulides

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 3 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

N. Y. Loh· 3 shared F. Karpe· 2 shared M. J. Neville· 2 shared M. Todorcevic· 2 shared M. Verma· 2 shared S. K. Vasan· 2 shared A. D. van Dam· 1 shared A. Wesolowska-Andersen· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersCell Biology

N. Y. Loh

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Author profile →

4 papers

Recent·Most cited

Two-pore channel 2 is a key regulator of adipocyte differentiation via the cAMP signaling pathway with calpain as downstream effector

Y. Zhang, L.-H. Chan, R. Tunn, M. Ruas, D. Gay, M. Todorcevic, C. Christodoulides, J. Parrington

This study identifies TPC2 as a key regulator of adipocyte differentiation via the cAMP signaling pathway, with calpain as a downstream effector, and links genetic variation to fat distribution.

bioRxiv · Mar 20, 2021 · PreprintCell Biology

LRP5 promotes adipose progenitor cell fitness and adipocyte insulin sensitivity

N. Y. Loh, S. K. Vasan, M. Verma, A. Wesolowska-Andersen, M. J. Neville, C. Osmond, C. L. Gregson, F. L. Karpe, C. Christodoulides

This study shows LRP5 enhances adipocyte insulin sensitivity and adipose progenitor cell fitness, with implications for obesity and aging.

bioRxiv · Mar 4, 2020Cell Biology

TCF7L2 plays a complex role in human adipose progenitor biology which may contribute to genetic susceptibility to type 2 diabetes.

M. Verma, N. Y. Loh, S. K. Vasan, A. D. van Dam, M. Todorcevic, M. J. Neville, F. Karpe, C. Christodoulides

This study investigates TCF7L2's role in adipose progenitor biology and links its genetic variation to type 2 diabetes risk through effects on adipogenesis and insulin sensitivity.

bioRxiv · Nov 26, 2019 · PreprintCell Biology

Associations between outdoor temperature and bright sunlight with metabolites in two population-based European cohorts

B. C. Eveleens Maarse, N. Y. Loh, F. Karpe, F. R. Rosendaal, D. van Heemst, D. O. Mook-Kanamori, K. Willems van Dijk, P. C. Rensen, S. Kooijman, C. Christodoulides, R. Noordam

This study examines how outdoor temperature and bright sunlight affect metabolite levels in two European cohorts, finding temperature increases linked to higher lipoprotein and amino acid levels, while bright sunlight is associated with lower very low density lipoprotein levels.

bioRxiv · Oct 30, 2019Physiology