Author

M. Todorcevic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

C. Christodoulides· 2 shared A. Arvaniti· 1 shared A. D. van Dam· 1 shared A. Moolla· 1 shared A. Odermatt· 1 shared C. L. Cummins· 1 shared C. Ohlsson· 1 shared D. Gay· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

C. Christodoulides

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Author profile →

3 papers

Recent·Most cited

Two-pore channel 2 is a key regulator of adipocyte differentiation via the cAMP signaling pathway with calpain as downstream effector

Y. Zhang, L.-H. Chan, R. Tunn, M. Ruas, D. Gay, M. Todorcevic, C. Christodoulides, J. Parrington

This study identifies TPC2 as a key regulator of adipocyte differentiation via the cAMP signaling pathway, with calpain as a downstream effector, and links genetic variation to fat distribution.

bioRxiv · Mar 20, 2021 · PreprintCell Biology

Akr1d1-/- mice have a sexually dimorphic metabolic phenotype with reduced fat mass, increased insulin sensitivity and hypertriglyceridemia in males

L. L. Gathercole, N. Nikolaou, A. Arvaniti, S. E. Harris, T. M. Poolman, J. M. Hazlehurst, D. V. Kratschmar, M. Todorcevic, A. Moolla, N. Dempster, R. C. Pink, M. F. Saikali, L. Bentley, T. M. Penning, C. Ohlsson, , J. W. Tomlinson

This study shows that AKR1D1 controls bile acid homeostasis and affects insulin sensitivity and lipid homeostasis in a sex-dependent manner in mice.

bioRxiv · Feb 2, 2021 · PreprintPhysiology

TCF7L2 plays a complex role in human adipose progenitor biology which may contribute to genetic susceptibility to type 2 diabetes.

M. Verma, N. Y. Loh, S. K. Vasan, A. D. van Dam, M. Todorcevic, M. J. Neville, F. Karpe, C. Christodoulides

This study investigates TCF7L2's role in adipose progenitor biology and links its genetic variation to type 2 diabetes risk through effects on adipogenesis and insulin sensitivity.

bioRxiv · Nov 26, 2019 · PreprintCell Biology