Author

P. C. Rensen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:metabolism & bioenergetics· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

S. Kooijman· 2 shared A. Park· 1 shared A.-C. Andreasson· 1 shared B. C. Eveleens Maarse· 1 shared B. Guigas· 1 shared B. Martinez· 1 shared B. Spoorenberg· 1 shared C. Christodoulides· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersPhysiology

S. Kooijman

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis

C. Liu, M. Schönke, B. Spoorenberg, J. Lambooij, H. van der Zande, E. Zhou, M. E. Tushuizen, A.-C. Andreasson, A. Park, S. Oldham, M. Uhrbom, I. Ahlstedt, Y. Ikeda, K. Wallenius, X.-R. Peng, , P. C. Rensen

This study shows that FGF21 overexpression in the liver reduces lipotoxicity, inflammation, and fibrosis in NASH by blocking lipid influx and macrophage activation.

bioRxiv · Sep 20, 2022Pathology

Cold exposure induces dynamic changes in circulating triacylglycerol species, which is dependent on intracellular lipolysis: a randomized cross-over trial

M. Straat, L. Jurado Fasoli, Z. Ying, K. J. Nahon, L. Janssen, M. Boon, G. Grabner, S. Kooijman, R. Zimmermann, M. Giera, P. C. Rensen, B. Martinez

This study shows cold exposure increases circulating free fatty acids and transiently lowers total triacylglycerols in humans, with dynamic changes in TAG species dependent on saturation and chain length, and this effect is mediated by intracellular lipolysis.

bioRxiv · Sep 9, 2022Physiology

Associations between outdoor temperature and bright sunlight with metabolites in two population-based European cohorts

B. C. Eveleens Maarse, N. Y. Loh, F. Karpe, F. R. Rosendaal, D. van Heemst, D. O. Mook-Kanamori, K. Willems van Dijk, P. C. Rensen, S. Kooijman, C. Christodoulides, R. Noordam

This study examines how outdoor temperature and bright sunlight affect metabolite levels in two European cohorts, finding temperature increases linked to higher lipoprotein and amino acid levels, while bright sunlight is associated with lower very low density lipoprotein levels.

bioRxiv · Oct 30, 2019Physiology