Combination of photoactivation with lattice light-sheet imaging reveals untemplated, lamellar ruffle generation by PA-Rac1
F. Leyden, S. Uthishtran, U. K. Moorthi, H. M. York, A. Patil, H. Gandhi, E. P. Petrov, S. Arumugam
The paper uses optogenetic PA-Rac1 and lattice light-sheet imaging to show Rac1 drives untemplated lamellar ruffle formation without a template.
bioRxiv · Sep 1, 2020 · PreprintBiophysics