Author

U. K. Moorthi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Assay:imaging· 3 Approach:microscopy & imaging analysis· 3 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Patil· 3 shared H. Gandhi· 3 shared S. Arumugam· 3 shared H. M. York· 2 shared A. Bhowmik· 1 shared A. Kaur· 1 shared C. Mitchell· 1 shared C. S. Wright· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBiophysics

A. Patil

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Deterministic Early Endosomal Maturations Emerge From a Stochastic Trigger-and-Convert Mechanism

H. M. York, K. Joshi, C. S. Wright, L. Z. Kreplin, S. Rodgers, U. K. Moorthi, H. Gandhi, A. Patil, C. Mitchell, S. Iyer-Biswas, S. Arumugam

The paper tracks endosomal maturation events using advanced imaging and simulations, revealing that maturation is driven by heterotypic EEA1-mediated interactions rather than autonomous stochastic processes.

bioRxiv · Apr 15, 2022Biophysics

Rapid Whole Cell Imaging Reveals A Calcium-APPL1-Dynein Nexus That Regulates Cohort Trafficking of Stimulated EGF Receptor

H. York, A. Patil, U. K. Moorthi, A. Kaur, A. Bhowmik, G. J. Hyde, H. Gandhi, K. Gaus, S. Arumugam

The paper uses whole-cell imaging to reveal a calcium-APPL1-dynein mechanism that directs EGFR trafficking to the peri-nuclear region.

Communications Biology · Feb 17, 2021Peer-reviewedCell Biology

Combination of photoactivation with lattice light-sheet imaging reveals untemplated, lamellar ruffle generation by PA-Rac1

F. Leyden, S. Uthishtran, U. K. Moorthi, H. M. York, A. Patil, H. Gandhi, E. P. Petrov, S. Arumugam

The paper uses optogenetic PA-Rac1 and lattice light-sheet imaging to show Rac1 drives untemplated lamellar ruffle formation without a template.

bioRxiv · Sep 1, 2020 · PreprintBiophysics