TGF-β Mediated Cell Adhesion Dynamics and Epithelial to Mesenchymal Transition in 3D and 2D Ovarian Cancer Models
W. Al Ameri, I. Ahmed, F. M. Al-Dasim, Y. Ali Mohamoud, I. K. Al-Azwani, J. A. Malek, T. Karedath
This study compares 3D and 2D ovarian cancer models to show TGF-β induces EMT, invasion, and aggressiveness, with reversible effects using a TGF-β inhibitor.
bioRxiv · Nov 8, 2018 · PreprintCancer Biology