Author

J. A. Malek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

I. Ahmed· 2 shared T. Karedath· 2 shared W. Al Ameri· 2 shared Y. Ali Mohamoud· 2 shared A. Rafii· 1 shared F. Al-Dasim· 1 shared F. M. Al-Dasim· 1 shared I. K. Al Azwani· 1 shared

Activity by Year

2018-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

I. Ahmed

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Deletion of beta-fructofuranosidase (invertase) genes is associated with sucrose content in Date Palm fruit

J. A. Malek, S. Mathew, L. S. Mathew, S. Younuskunju, Y. A. Mohamoud, K. Suhre

The paper identifies a deletion of two beta-fructofuranosidase genes in high-sucrose date palm cultivars and links it to sucrose content in dried fruit.

bioRxiv · May 29, 2019Plant Biology

TGF-β Mediated Cell Adhesion Dynamics and Epithelial to Mesenchymal Transition in 3D and 2D Ovarian Cancer Models

W. Al Ameri, I. Ahmed, F. M. Al-Dasim, Y. Ali Mohamoud, I. K. Al-Azwani, J. A. Malek, T. Karedath

This study compares 3D and 2D ovarian cancer models to show TGF-β induces EMT, invasion, and aggressiveness, with reversible effects using a TGF-β inhibitor.

bioRxiv · Nov 8, 2018 · PreprintCancer Biology

Silencing of ANKRD12 circRNA induces molecular and functional changes associated with invasive phenotypes

T. Karedath, I. Ahmed, W. Al Ameri, F. Al-Dasim, S. S. Andrews, S. Samuel, I. K. Al Azwani, Y. Ali Mohamoud, A. Rafii, J. A. Malek

This study identifies circANKRD12 as a circular RNA that promotes cancer invasion by regulating cell cycle, migration, and metabolism when silenced.

bioRxiv · Jul 10, 2018Cancer Biology