Therapeutic efficacy of an immune stimulatory gene therapy strategy in a mouse model of high grade brainstem glioma
F. M. Mendez, P. Kadiyala, F. J. Nunez, S. Carney, F. Nunez, J. C. Gauss, R. Ravindran, S. Pawar, M. Edwards, P. Lowenstein, M. G. Castro
This paper tests an immune-stimulatory gene therapy in a mouse model of DIPG, showing increased survival and anti-tumor immunity through adenoviral delivery of TK and Flt3L.
bioRxiv · Nov 18, 2019 · PreprintCancer Biology