Author

F. Marinelli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:protein folding & dynamics· 3 Approach:statistical model· 3 Approach:deep learning· 2 Research Focus:benchmarking· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:multiome· 1 Assay:proteomics· 1

Frequent Co-Authors

J. D. Faraldo-Gomez· 3 shared H. J. Choi· 1 shared J. Faraldo-Gomez· 1 shared J. Lee· 1 shared L. R. Forrest· 1 shared M. Kim· 1 shared R. K. Hite· 1 shared R. T. Bradshaw· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiophysics

J. D. Faraldo-Gomez

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Conformational free-energy landscapes of a Na+/Ca2+ exchanger explain its alternating-access mechanism and functional specificity

F. Marinelli, J. D. Faraldo-Gomez

This paper uses simulations to map the free-energy landscapes of a Na+/Ca2+ exchanger, explaining its antiporter function, specificity, and 3:1 stoichiometry.

bioRxiv · Jan 20, 2023 · PreprintBiophysics

Differential ion dehydration energetics explains selectivity in the non-canonical lysosomal K+ channel TMEM175

S. Oh, F. Marinelli, W. Zhou, J. Lee, H. J. Choi, M. Kim, J. D. Faraldo-Gomez, R. K. Hite

The paper investigates the ion selectivity mechanism of TMEM175, showing that its unique hydrophobic constriction and electrostatic field enable K+ selectivity without a canonical filter.

bioRxiv · Nov 5, 2021Biophysics

Force-correction Analysis Method for Derivation of Multidimensional Free Energy Landscapes from Adaptively Biased Replica Simulations

F. Marinelli, J. Faraldo-Gomez

This paper introduces FCAM, a method to calculate multidimensional free-energy landscapes from biased molecular dynamics simulations, showing it outperforms existing methods in accuracy and convergence.

bioRxiv · Feb 17, 2021Biophysics

Structural Interpretation of Hydrogen-Deuterium Exchange with Maximum-Entropy Simulation Reweighting

R. T. Bradshaw, F. Marinelli, J. D. Faraldo-Gomez, L. R. Forrest

This paper introduces HDXer, a method to generate structural ensembles from HDX-MS data using maximum-entropy reweighting, demonstrating its ability to recover accurate structural information from simulated data.

bioRxiv · Sep 14, 2019Biophysics