Cell BiologybioRxiv
Unrestrained ESCRT-III drives chromosome fragmentation and micronuclear catastrophe
M. Vietri, S. W. Schultz, A. Bellanger…·C. Campsteijn
This study shows that unrestrained ESCRT-III activity at micronuclei causes chromosome fragmentation and DNA damage, while it facilitates repair in primary nuclei.
DOI 10.1038/s41556-020-0537-5