C. M. Jones

MYC is sufficient to generate mid-life high-grade serous ovarian and uterine serous carcinomas in a p53-R270H mouse model

This paper shows that combining MYC and p53-R270H mutations in a mouse model generates high-grade serous ovarian and uterine serous carcinomas with human-like genetic and transcriptomic features.

Small dams drive Anopheles abundance during the dry season in a high malaria burden area of Malawi

This study investigates how small dams affect malaria vector abundance during the dry season in Malawi, finding that proximity to dams significantly increases Anopheles mosquito densities.

Predicting genomic traits in ammonia-oxidizing archaea using phylogenetic signals

The paper predicts genomic traits in ammonia-oxidizing archaea using phylogenetic signals, finding 94% of genes show significant phylogenetic signal with high prediction accuracy.

Phyloecology of nrfA-ammonifiers and their relative importance with denitrifiers in global terrestrial biomes

The paper examines the phyloecology of nrfA-ammonifiers and their role compared to denitrifiers in global terrestrial biomes, finding they dominate except in tundra and are influenced by nitrate rather than carbon content.

Distribution and environmental drivers of fungal denitrifiers in global soils

This study investigates the distribution and environmental drivers of fungal denitrifiers in global soils, finding they are sparse but cosmopolitan, with specific abundance patterns in certain biomes and soil types.

Engineered RecA constructs reveal the minimal SOS activation complex

This study identifies the minimal RecA* filament required for LexA cleavage by showing that three linked RecA units can bind ssDNA and trigger LexA degradation.

Using Shape Fluctuations to Probe the Mechanics of Stress Granules

This study introduces a high-throughput flicker spectroscopy technique to measure surface tension in stress granules, revealing deviations from simple liquid droplet behavior.

The human-baited host decoy trap (HDT) is an efficient sampling device for exophagic malaria mosquitoes within irrigated lands in southern Malawi

The paper compares the effectiveness of the Host Decoy Trap (HDT) with other traps for sampling Anopheles arabiensis in southern Malawi, finding HDT to be as effective as Human Landing Catch.

An improved fluorescent noncanonical amino acid for measuring conformational distributions using time-resolved transition metal ion FRET

This paper introduces an improved fluorescent noncanonical amino acid, Acd, for time-resolved tmFRET to measure conformational distributions in proteins.

Genetic Encoding of a Highly Photostable, Long Lifetime Fluorescent Amino Acid for Imaging in Mammalian Cells

The paper introduces a genetically encodable fluorescent amino acid, Acd, with superior photostability and long fluorescence lifetime for use in FLIM and protein studies.

The application of drones for mosquito larval habitat identification in rural environments: a practical approach for malaria control?

This paper evaluates the use of drone imagery for identifying mosquito larval habitats in rural Malawi, finding high accuracy with GeoOBIA but noting technical challenges.

Genetic diversity of Anopheles coustani in high malaria transmission foci in southern and central Africa

This study examines genetic variation and malaria transmission potential of Anopheles coustani in high transmission areas of Zambia and the DRC.

Unrestrained ESCRT-III drives chromosome fragmentation and micronuclear catastrophe

This study shows that unrestrained ESCRT-III activity at micronuclei causes chromosome fragmentation and DNA damage, while it facilitates repair in primary nuclei.

Relief of the Dma1-mediated checkpoint requires Dma1 autoubiquitination and dynamic localization

This study shows that Dma1's transient removal from SPBs during anaphase B, driven by auto-ubiquitination, is essential for silencing the Dma1-dependent mitotic checkpoint in fission yeast.