An Arf/Rab cascade controls the growth and invasiveness of glioblastoma
G. Kulasekaran, M. Chaineau, V. E. Piscapo, F. Verginelli, M. Fotouhi, M. Girard, Y. Tang, R. Dali, R. Lo, S. Stifani, P. S. McPherson
This study shows that loss of Rab35 or Arf5 in glioblastoma cells increases tumor growth and invasiveness by activating the epidermal growth factor receptor and upregulating SPOCD1.
bioRxiv · Apr 30, 2020Cancer Biology