Author

G. Kulasekaran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:proteomics· 1

Frequent Co-Authors

P. S. McPherson· 3 shared A. Aguila· 2 shared M. Khan· 2 shared R. Kumar· 2 shared V. Francis· 2 shared E. Banks· 1 shared F. Verginelli· 1 shared M. Chaineau· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCell Biology

P. S. McPherson

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3 papers

Recent·Most cited

DENND6A couples Arl8b to a Rab34/RILP/dynein complex regulating retrograde lysosomal trafficking and autophagy

R. Kumar, V. Francis, M. Khan, A. Aguila, G. Kulasekaran, P. S. McPherson

This study identifies DENND6A as a Rab34 GEF that couples with Arl8b to regulate lysosomal retrograde trafficking and autophagy.

bioRxiv · Aug 21, 2023 · PreprintCell Biology

DENND2B activates Rab35 at the intercellular bridge regulating cytokinetic abscission and tetraploidy

R. Kumar, V. Francis, M. S. Ioannou, A. Aguila, E. Banks, G. Kulasekaran, M. Khan, P. S. McPherson

This study identifies DENND2B as a Rab35 GEF that regulates cytokinetic abscission and prevents tetraploidy by modulating actin dynamics and the NoCut checkpoint.

bioRxiv · Jan 12, 2023Cell Biology

An Arf/Rab cascade controls the growth and invasiveness of glioblastoma

G. Kulasekaran, M. Chaineau, V. E. Piscapo, F. Verginelli, M. Fotouhi, M. Girard, Y. Tang, R. Dali, R. Lo, S. Stifani, P. S. McPherson

This study shows that loss of Rab35 or Arf5 in glioblastoma cells increases tumor growth and invasiveness by activating the epidermal growth factor receptor and upregulating SPOCD1.

bioRxiv · Apr 30, 2020Cancer Biology