Epigenome-wide association study for dilated cardiomyopathy in left ventricular heart tissue identifies putative gene sets associated with cardiac development and early indicators of cardiac risk
Konstanze Tan, Darwin Tay, Wilson Lek Wen Tan, Hong Kiat Ng, Eleanor Wong, Michael P. Morley, Gurpreet Kaur Singhera, Pritesh Jain, Fei Li Tai, Paul Hanson, Thomas P. Cappola, Kenneth B. Margulies, Roger Foo, Marie Chiew Shia Loh
This study identifies 194 epigenome-wide significant CpGs associated with dilated cardiomyopathy (DCM) and links them to cardiac gene expression and cardiovascular risk factors.
medRxiv · Jul 16, 2024 · PreprintGenetic & Genomic Medicine