Tumor extracellular vesicles are required for tumor-associated macrophage programming
Daniel C Rabe, Felicia D Rustandy, Jiyoung Lee, Marsha Rich Rosner
This study shows tumor extracellular vesicles are necessary and sufficient for programming tumor-associated macrophages toward a pro-metastatic phenotype through CCL5 and TLR signaling.
bioRxiv · Jul 23, 2018 · PreprintCancer Biology