Lysine Potentiates Insulin Secretion via AASS-Dependent Catabolism and Regulation of GABA Content and Signaling
Felipe Muñoz, Qian Gao, Matthias Mattanovich, Kajetan Trôst, Ondřej Hodek, Andreas Lindqvist, Nils Wierup, Malin Fex, Thomas Möritz, Hindrik Mulder, Luis Rodrigo Cataldo
This study shows lysine enhances insulin secretion through AASS-dependent catabolism, which regulates GABA content and mitochondrial function in beta cells.
bioRxiv · Mar 3, 2025 · PreprintCell Biology