Author

Nils Wierup

Lund UniversityORCID 0000-0001-6824-4093Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Emilia Ottosson-LaaksoiD· 2 shared Hindrik MulderiD· 2 shared Leif GroopiD· 2 shared Malin FexiD· 2 shared Ola HanssoniD· 2 shared Andreas LindqvistiD· 1 shared Claes B. WollheimiD· 1 shared Claes Wollheim· 1 shared

Activity by Year

2014-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMolecular Biology

Emilia Ottosson-LaaksoORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintMar 3, 2025

Lysine Potentiates Insulin Secretion via AASS-Dependent Catabolism and Regulation of GABA Content and Signaling

Felipe Muñoz, Qian Gao, Matthias Mattanovich…·Luis Rodrigo Cataldo

This study shows lysine enhances insulin secretion through AASS-dependent catabolism, which regulates GABA content and mitochondrial function in beta cells.

1 citation

humanmetabolomics

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Molecular BiologyLife Science AlliancePeer-reviewedAug 10, 2022

Islet Gene View - a tool to facilitate islet research

Olof Asplund, Petter Storm, Vikash Chandra…·Rashmi B. Prasad

The paper introduces Islet Gene View (IGW), a platform that integrates gene expression and phenotypic data from pancreatic islets to explore T2D-related gene expression changes and their functional implications.

53 citationstop 1%

humanbulk RNA-seq

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Cell BiologybioRxivMar 5, 2014

TCF7L2 is a master regulator of insulin production and processing

Yuedan Zhou, Soo-Young Park, Jing Su…·Ola Hansson

This study identifies TCF7L2-target genes and their regulatory network in insulin secretion, showing TCF7L2 regulates proinsulin synthesis, processing, and clearance in rodents and human islets.

DOI 10.1093/hmg/ddu359

mousehuman

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