Molecular BiologyChemBioChemPeer-reviewed
Core-shell DNA-cholesterol nanoparticles exert lysosomolytic activity in African trypanosomes
Robert Knieß, W.‐Matthias Leeder, Paul Reißig…·H. Ulrich Göringer
The paper describes DNA-cholesterol nanoparticles that kill Trypanosoma brucei by disrupting lysosomal membrane integrity and demonstrate a dual-target approach using DNAzymes.