Author

Fiona Roche

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell-cell communication· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Xavier NicoliD· 3 shared Claudia Gomez-BravoiD· 2 shared Juliette VougnyiD· 2 shared Sarah BaudetiD· 2 shared Sinthuya Uthayasuthan· 2 shared Yvrick ZagariD· 2 shared Adrien AntkowiakiD· 1 shared Akbar ZainuiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersDevelopmental Biology

Xavier NicolORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Temporal tuning of actin nucleation by the repurposed DNA repair complex RAD51/fignl1 encodes distinct axon guidance decisions

Samya Zerkoune, Yvrick Zagar, Julie Delaroche, Julia Danicka, Juliette Vougny, Sinthuya Uthayasuthan, Julien Aureille, Fiona Roche, Rhanna Haantjes, Claudia Gomez-Bravo, Sarah Baudet, Éric Denarier, Akbar Zainu, Philippe Bun, Xavier Guillonneau, , Coralie Fassier

The paper shows how RAD51/fignl1, repurposed from DNA repair, controls axon guidance by modulating F-actin nucleation timing and magnitude.

bioRxiv · Oct 18, 2026 · PreprintNeuroscience

CXCL12 targets the primary cilium cAMP/cGMP ratio to regulate cell polarity during migration

Melody Atkins, Maud Wurmser, Michèle C. Darmon, Fiona Roche, Xavier Nicol, Christine Métin

The paper shows that CXCL12 modulates the ciliary cAMP/cGMP ratio to control cell polarity and directed migration in cortical interneurons.

Nature Communications · Dec 4, 2023Peer-reviewedDevelopmental Biology

Subcellular second messenger networks drive distinct repellent-induced axon behaviors

Sarah Baudet, Yvrick Zagar, Fiona Roche, Claudia Gomez-Bravo, Sandrine Couvet, Johann Bécret, Morgane Belle, Juliette Vougny, Sinthuya Uthayasuthan, Oriol Ros, Xavier Nicol

The paper shows that repellent cues ephrin-A5 and Slit1 induce spatially segregated second messenger signals, controlling distinct axonal behaviors.

Nature Communications · Jun 27, 2023Peer-reviewedDevelopmental Biology