Philippe Bun

Temporal tuning of actin nucleation by the repurposed DNA repair complex RAD51/fignl1 encodes distinct axon guidance decisions

The paper shows how RAD51/fignl1, repurposed from DNA repair, controls axon guidance by modulating F-actin nucleation timing and magnitude.

Adhesion to a common ECM mediates interdependence in tissue morphogenesis in Drosophila

The paper shows that adhesion to a common ECM coordinates tissue morphogenesis in Drosophila by linking epidermal and tracheal cells through mechanical forces.

Cell-autonomous mitochondrial calcium flux governs oligodendrocyte regeneration

This study identifies mitochondrial calcium flux as a critical regulator of oligodendrocyte regeneration, showing its role in proliferation, differentiation, and lesion site repopulation.

ExoJ: an ImageJ2/Fiji plugin for automated spatiotemporal detection and analysis of exocytosis

ExoJ is an ImageJ2/Fiji plugin that automates the detection and analysis of exocytosis events, providing quantitative features and robust performance across varying signal-to-noise ratios.

Versatile and automated workflow for the analysis of oligodendroglial calcium signals in preclinical mouse models of myelin repair

The paper introduces an automated workflow and software tools for analyzing oligodendroglial calcium signals in mouse myelin repair models, revealing uncorrelated spontaneous Ca2+ activity in demyelinated lesions.