Xavier Guillonneau

The paper shows how RAD51/fignl1, repurposed from DNA repair, controls axon guidance by modulating F-actin nucleation timing and magnitude.

This study shows diesel exhaust particles impair microglial function and amyloid-beta clearance in both mouse and human models, potentially contributing to Alzheimer's disease progression.

This study develops a mouse model of hypertensive emergency with multiorgan microvascular disease and identifies dysregulated VEGFA/sFlt-1 signaling as a key driver.

This study shows that reduced vagal signaling increases AMD risk by promoting splenic monocyte infiltration into the retina, with splenectomy reversing these effects.