Éric Denarier

Temporal tuning of actin nucleation by the repurposed DNA repair complex RAD51/fignl1 encodes distinct axon guidance decisions

The paper shows how RAD51/fignl1, repurposed from DNA repair, controls axon guidance by modulating F-actin nucleation timing and magnitude.

VASH1 phosphorylation regulates tubulin detyrosination via CNP/PRKG1α signaling in DRG neurons.

This study identifies VASH1 phosphorylation by PRKG1 as a mechanism regulating tubulin detyrosination in DRG neurons through CNP signaling.

The Mn-motif protein MAP6d1 assembles ciliary doublet microtubules

This study identifies MAP6d1 as a microtubule-associated protein that assembles ciliary doublet microtubules by recruiting tubulin dimers and promoting luminal protofilament formation.

ALG-2 interacting protein-X (Alix) is required for activity-dependent bulk endocytosis at brain synapses

This study shows that Alix is required for activity-dependent bulk endocytosis at brain synapses, and its absence reduces seizure severity in mice.

AutoNeuriteJ: An ImageJ plugin for measurement and classification of neuritic extensions

AutoNeuriteJ automates neurite measurement and classification in neuronal cultures, detecting phenotypic differences in mouse neurons.

Presynaptic APP levels and synaptic homeostasis are regulated by Akt phosphorylation of Huntingtin

This study shows that Akt phosphorylation of Huntingtin regulates axonal transport of APP and presynaptic levels, affecting synaptic homeostasis and learning.