Florencia Rosetti

TGF-b/TIF1g signaling restrains CD8+ T cell expansion while preserving cytotoxic competence

This study identifies TIF1g as a regulator of TGF-b signaling in CD8+ T cells, showing it restricts expansion while preserving cytotoxic function.

TIF1γ regulates stability of T regulatory cells during inflammation

This study shows that TIF1γ maintains T regulatory cell stability and suppressor function during inflammation by regulating Foxp3 expression and the beta-catenin pathway.

A novel risk score model based on seven protein-coding genes and three pseudogenes predicts overall survival in acute myeloid leukemia

This study develops a risk score model using seven protein-coding genes and three pseudogenes to predict overall survival in acute myeloid leukemia, showing significant survival differences between risk groups.

Gene expression profiling of dendritic cell tolerance dysfunction in women with Systemic lupus erythematosus

The paper identifies transcriptional disruptions in dendritic cells from SLE patients, highlighting interferon-driven changes, impaired IL-10 signaling, and altered lipid metabolism as key factors in tolerance dysfunction.