Author

Paula Licona Limon

Instituto de Fisiologia Celular, Universidad Nacional Autonoma de MexicoORCID 0000-0002-7692-8900Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Florencia Rosetti· 2 shared Jose Luis Ramos-Balderas· 2 shared Vesa KaartineniD· 2 shared Alfredo Ibarra-Sanchez· 1 shared Andres CabezasiD· 1 shared Araceli Pérez-LópeziD· 1 shared Aurora Candelario‐Martínez· 1 shared Claudia Gonzalez-Espinosa· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Florencia Rosetti

Mutual co-authors in cluster

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2 papers

Recent·Most cited

TGF-b/TIF1g signaling restrains CD8+ T cell expansion while preserving cytotoxic competence

Jesus Daniel Zambrano-Romero, Eugenio Contreras-Castillo, Veronica Yutsil Garcia-Rasilla, Ma Cleofas Marcial-Medina, Diana Berenice Rios-Ramirez, Jose Luis Ramos-Balderas, Javier Orozco-Cordoba, Luis Tenorio-Hernandez, Alfredo Ibarra-Sanchez, Diego Delgado-Saldivar, Harumichi Ishigame, Maria Carolina Amezcua-Vesely, Claudia Gonzalez-Espinosa, Florencia Rosetti, Jose C. Crispin, , Paula Licona Limon

This study identifies TIF1g as a regulator of TGF-b signaling in CD8+ T cells, showing it restricts expansion while preserving cytotoxic function.

bioRxiv · Nov 6, 2026 · PreprintImmunology

TIF1γ regulates stability of T regulatory cells during inflammation

Eugenio Contreras-Castillo, Jesús Daniel Zambrano-Romero, Hober Nelson Núñez-Martínez, Cleofas Marcial-Medina, Javier Orozco-Cordoba, Diana Berenice Ríos-Ramírez, Ofelia Muñoz-Paleta, Diego Pérez-Vázquez, Andres Cabezas, María Guadalupe García-Patiño, Jose Luis Ramos-Balderas, Gustavo Tapia-Urzúa, Luis Tenorio-Hernández, Georgina Guerrero, Nallely Cano-Domínguez, , Paula Licona-Limón

This study shows that TIF1γ maintains T regulatory cell stability and suppressor function during inflammation by regulating Foxp3 expression and the beta-catenin pathway.

Nature Immunology · Aug 11, 2026Peer-reviewedImmunology