Gene expression profiling of dendritic cell tolerance dysfunction in women with Systemic lupus erythematosus
Ana Laura Hernández-Ledesma, Evelia Lorena Coss-Navarrete, Sofia Salazar-Magaña…·Alejandra Medina-Rivera
The paper identifies transcriptional disruptions in dendritic cells from SLE patients, highlighting interferon-driven changes, impaired IL-10 signaling, and altered lipid metabolism as key factors in tolerance dysfunction.