Glycan-induced structural activation softens the human papillomavirus capsid for entry through reduction of intercapsomere flexibility
Yuzhen Feng, Dominik van Bodegraven, Alan Kádek, Ignacio L. B. Munguira, Laura Soria-Martinez, Sarah Nentwich, Sreedeepa Saha, Florian Chardon, Daniel Kavan, Charlotte Uetrecht, Mario Schelhaas, Wouter H. Roos
This study investigates how glycan-induced structural activation of the HPV capsid facilitates entry by reducing intercapsomere flexibility.
bioRxiv · Feb 1, 2024Microbiology