Charlotte Uetrecht

The paper investigates how specific mutations in the SARS-CoV-2 N/ORF9b gene affect host immune responses and infection outcomes using recombinant viruses.

The paper uses integrated mass spectrometry to show AMPK phosphorylation occurs through hierarchical proteoform cascades with specific kinetic priorities and regulatory control.

This study identifies CAPRIN1's localization to MVB-like egress compartments in SARS-CoV-2 infection and shows its role in limiting cytopathic effects.

The paper uses statistical crystallography to model correlated motions in SARS-CoV-2 Mpro and shows how dimerization affects catalytic activity through structural links.

This study compares two CDMS methods to analyze norovirus capsid assembly, revealing non-classical mass distributions in GII.17 Kawasaki capsids confirmed by cryo-EM.

This study uses integrated top-down mass spectrometry to reveal structural heterogeneity in AMPK proteoform-ligand complexes, uncovering new insights into kinase regulation.

This paper introduces a fast-track affinity purification workflow that skips buffer exchange, enabling direct nMS analysis and improving protein recovery for challenging proteins.

This paper discusses the use of X-ray spectroscopy and native mass spectrometry to study gas-phase protein complexes, showing fragmentation and dissociation patterns under different activation methods.

This study investigates how glycan-induced structural activation of the HPV capsid facilitates entry by reducing intercapsomere flexibility.

The paper investigates clathrin binding selectivity among yeast adaptor proteins, finding Ent5 has the highest affinity and Ent1 shows stronger clathrin interaction than Ent2.

This paper develops an automated high-throughput platform for DNA aptamer selection using an optical next-generation sequencer, achieving higher affinity aptamers in fewer rounds than conventional SELEX.

The paper quantifies the kinetics of SARS-CoV-2 polyprotein processing and its impact on RTC complex formation using native MS.