Author

Francesca Froldi

The University of Melbourne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:Drosophila· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Louise Y ChengiD· 3 shared John P. D. McMulleniD· 2 shared Owen J. MarshalliD· 2 shared Phuong‐Khanh NguyeniD· 2 shared Qian DongiD· 2 shared Edel Alvarez‐OchoaiD· 1 shared Kellie VeeniD· 1 shared Kieran F. HarveyiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersDevelopmental Biology

Louise Y ChengORCID

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3 papers

Recent·Most cited

Chinmo defines the region-specific oncogenic competence in the Drosophila central nervous system

Phuong‐Khanh Nguyen, Francesca Froldi, John P. D. McMullen, Tony D. Southall, Owen J. Marshall, Louise Y Cheng

The paper shows that oncogenic outcomes of dedifferentiation in Drosophila CNS vary by region, mediated by Chinmo and ecdysone signaling.

Proceedings of the National Academy of Sciences · May 20, 2026Peer-reviewedDevelopmental Biology

Cell cycle and temporal transcription factors regulate proliferation and neuronal diversity of dedifferentiation-derived neural stem cells

Kellie Veen, Francesca Froldi, Qian Dong, Edel Alvarez‐Ochoa, Phuong‐Khanh Nguyen, Kieran F. Harvey, John P. D. McMullen, Owen J. Marshall, Patricia Regina Jusuf, Louise Y Cheng

This study shows that dedifferentiation-derived neural stem cells (NSCs) fail to express late temporal transcription factors, leading to impaired neuronal diversity and cell cycle progression.

bioRxiv · Jul 24, 2022 · PreprintDevelopmental Biology

Glial Hedgehog and lipid metabolism regulate neural stem cell proliferation in Drosophila

Qian Dong, Michael Zavortink, Francesca Froldi, Sofya Golenkina, Tammy Lam, Louise Y Cheng

This study shows that glial Hedgehog signaling and lipid metabolism regulate neural stem cell proliferation in Drosophila by modulating Hh signaling through lipid droplets and palmitoylation.

EMBO Reports · Mar 10, 2021Peer-reviewedDevelopmental Biology