John P. D. McMullen

The paper shows that oncogenic outcomes of dedifferentiation in Drosophila CNS vary by region, mediated by Chinmo and ecdysone signaling.

The paper shows that GAL4 driver expression in Drosophila declines rapidly with age, with some drivers losing activity within 30 days.

The paper identifies eight chromatin states in Drosophila that segregate the genome into developmental and housekeeping roles through chromatin protein and histone mark associations.

This study shows that dedifferentiation-derived neural stem cells (NSCs) fail to express late temporal transcription factors, leading to impaired neuronal diversity and cell cycle progression.

The paper introduces FlyORF-TaDa, a system that rapidly generates transgenic Drosophila lines for cell-type specific profiling of protein-DNA interactions using existing FlyORF libraries.

The paper introduces new TaDa vectors that enable simultaneous profiling of protein-DNA interactions and visualization of expression domains using membrane-bound GFP or mCherry labels.